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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80951c4bd42cc961e56feb69df65488f7c11e00fca1b71e0726a077e09a9ec4e' 
  AND token = 'z6TsgA/RSyJmb/Wa2cR/yaZW8HJ+YCl4ZA/4MUGu6aM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}