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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4446959e0463e023ff0fa69b327b154e53c64988235a33f90e067ffc11c24100' 
  AND token = 'tf7F4/mFYNtg0hgBd+7STL7+mUKHnE6eVEyDHIC1mO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}