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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2921fb1937d3a65b6c4da6a26fc1d7f091f89ba5a2f49e09e1d231810057ff10' 
  AND token = 'vG+eHR2m+ciMspzkTusVwZQsfOBcfihedg4X05GiL14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}