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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2736cfcd4ad9e4ead434c188dc8c68c6c1190bfe3d129bd31019b9ff514871' 
  AND token = 'QsCT6rmOq/XEJ4EG8JjojnK+QU/yc8mHVTM07Kpl+6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}