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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8cb27a8150e7a322ee3b1aeaa45851a7b4b8bd2faf6ff3dbc4e187fb9daa86' 
  AND token = 'z7ESS9OVhM0QS9eN1fds/gtMDbB0BFwU9dW6kJJ0MUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}