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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9070821b1a157c66280de0a3bf9531e68caec0e98ecf4a51c0f3a31b6929934f' 
  AND token = 'toG3mO9GW6qNH567jdxJ+pNHexeRXAFe3Xm2EgA47Ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}