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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05c2172a13ce36a664615c4d4ef26ed22cd8c6e5d9ac69bcfab85dd41d7eb601' 
  AND token = '4aq/M1eiYU/u1vk3bRoCFVu7Tre7ocq1Febma+4qQOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}