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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01aedf0db973aba4e9a2390e5c02f1d0601cddb91b1f527a8c52c4a8ac9e551c' 
  AND token = 'fYEQ9r+a7K8v90V4i1p3M+dRbQaTuGxM5W9t4QvprLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}