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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94d4411b5f98dffa01153e361cb9e959dc83a68b3c990d7cebb0d0856a07b46c' 
  AND token = 'YEuz+rWZCOR6z72c6DpCaXldaaVBwM9TuMjMGUBRt0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}