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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a77dd26467dbf2c74f5eb73da8def968fed7a2b7f0035c966dba0c65c4e13c86' 
  AND token = 'Duh/ljI89TC0MEQ4IO9/+sAt/gmxrFxDgS+tFsmXNAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}