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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2f1e5914dec4a072cd2b8696538c4ece016b5e9507bc4b2cd3b9ef37dfa64d' 
  AND token = 'GUvDd9b9T/cUGx6C6FWnDqOA1PVprRm62uhh+dzyXiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}