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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '614e49a02959c7e9079f34d46018477ad24bef15bd468a4e31bbd467d882e94f' 
  AND token = '+TST4Zrq2EvRVp0lJVx2NfvDr+bE2GCi+oy48BM2pmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}