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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ff53041c581f36cd15886a2749289f549a55dc9b1c1e79c18996b03531b59bb' 
  AND token = 'mpZ5nMef/WrNcqHkHL6/9yRs+sv5lKytfTFgtGPsoOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}