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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfca103bcb809c647b3e839c4e69ef55832c273ffc02c307ca2fae4bc2be5a21' 
  AND token = '0L22aTNy6hHn7UxxmiKckYn/OqxvskP2kjA+Ikv9BoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}