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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1af8d8aa7861e8dc565e84a5d2bf441c6e81a2578fe243194486c5fcc3924f45' 
  AND token = 'G+x4ppUHJhJe14uFSw76ekQ+NbI4tVJ9HKhcwpkINww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}