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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29e0258a3c36d00a801e1e84fcc43becce848967297865a1b404a2b1f77f4c0b' 
  AND token = 'DagigQQuXq/kvT/IyUJensgQBY9dPu1j99AuHJDG04Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}