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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c642359d2c054f0d94b0407bdaca72ed0b8633fd423ff2a984d0c2ab51ed01e4' 
  AND token = 'ORvvqkUhxp00l3DAg1cGEy76mkFWjgefFEoF0ShRw1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}