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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c22336bcb045f443a31ba40331cd5ecca8777964ac509cca1531cdc6fe1f56' 
  AND token = 'hKRK8dPQaqLPrVG3vJPCmIJdnNf9m16FZR0pN715spg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}