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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3a72f8ffbc7f5a051cd6a924f26909001d6f48d2f734152ce62f6e5f455d7c' 
  AND token = '2W5XaJtHqs1rp4PfniYTrIVlA9S8IhwEpFfN8/PdN3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}