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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57114b2e00c53f994a9b6061cbb718f653ee0ecd8e3169720c9125265c8be0e0' 
  AND token = 'BpxCjFRlXnIhIKrSA6fdzu/YUrZRrXxQaJWUkHZDD7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}