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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f39825f4966f77ae28e637380545302f2294539eb6d196914a9f71231d97950a' 
  AND token = 'xcUKkYNywiZ8G8d81trar0h5heN3BCFfw2UXsSINts8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}