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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e73546a91a185e38c88a891b59397fc75202ef10130f9911100cabfa91a25e0' 
  AND token = 'LG28kHM7q8Doy+V8CnGIkLbljgPviRsC+av44fqpWCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}