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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2249acd2b192f3ab8d449e951a6d6475d239affe1e52cec373ac9830f66f21f4' 
  AND token = 'aHZZ5GykHKG4qpMObeLmzkCTfKJYOL8PDbRLpOrR5YY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}