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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b43c8a96f99d44599acf66587ade47d6c96775fd6dd55ba2010a9f0e522e5dcf' 
  AND token = 'V71qRCDB5KOP8/aRT9kixpir6idY6PJbW886iB0ksuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}