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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5405e36dd6a670b0c67bccb943dd15f2dd9bd30a52a76af131eae913e54e33e4' 
  AND token = 'W1s0M3H2gI0XsZoV4YFN0ayAY413Qf/v4AfZfEcROuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}