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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ce8abf6393d2abe15d9b81effd9ccdf72345b781b6f6b58274ebf805439b787' 
  AND token = 'wd0Qd9p+GM7L0c7EL8LJi90mOGgSY5Lu1PFA3BsKVmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}