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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '531050d2bbce4578231f2164a481bc13765cee2071c3169d72abb64e9f3e9270' 
  AND token = 'Rkv4IZTmEQC84IQ/MetulpifKOdqWM/3/q8Yvtk+SbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}