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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66010ac4c64a1663f0e0fbee74356edcf7a1e4c0814015d7577a05477d44517a' 
  AND token = 'YNAKtIXmCPyR7MO2DB9qsWYv6Umrq8KZoEVXc2/oGsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}