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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7603a60f3bff00283ade04c54b519e4876428f33e24a7757a3660c76e991344' 
  AND token = 'J1F5sAi2qxlXVfW3mljWMdnaYda2XIVMYI7skw2yYLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}