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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4999f527ae13c5df1139df2a3eb81aee689a5f6c11bb6314d30be9f0e3f6a344' 
  AND token = 'vViqvjPTAVYDx6rnN26kqAcu+0ZwfWl6RldFOAXXCj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}