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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f6109793907100468689274ac882cea7ab38f902a563b8f95e7fbd699127f7c' 
  AND token = 'TWWDsGW2a1z9ZeV/Z/NIPmH2L4vT7L6i6erlR79PyxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}