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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45cf80b09aa425ac0fc5c19c18f0de4805c4ca79d2e02d2ecfbd75318eefe0b5' 
  AND token = '6paVC1Pb1lQwff3kSaiT+JYxA4teoVKClUuiNZ0IYec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}