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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abe78bd19e890022bce213a2f41407e8b06a30560af48e12b0326119b85499dd' 
  AND token = '2Q0la1Zintr++PJDl2rAJh2vf9H7vtBfhLwGVqXg6nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}