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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2fe0230f5b0c05026c1bfa9e24d45137548cb204436f3490954a18ee9e6b426' 
  AND token = 'zAQuo7rMdXG65/As431A0oiitgMq1xGX2gUb0SkBHAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}