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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00fe081736fddacc840adfffd8a4067d0286ad6ec564c5c3fbb10f725a3708b6' 
  AND token = 'UC3FWqXWNsl1hn7BgI9MLxznrIrJwksKBwsNkdz7HLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}