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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b26fc36c11ee98c95b532e99f3924a9bc7c94e8f04ea50051b18b18e6d47bf41' 
  AND token = 'gD3qAcO3xRbFKbeHHadA6sYJyCgv6OfF8wPYZ0vEz5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}