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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '397e02b2c954ac834852f2b3a72988bd9aa1b0834a062a2b3a2f895aae4ab638' 
  AND token = 'OAYWRByPAtHwknAsRGFJ2kObL3lSB9TOpZBkjp7kaIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}