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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78aea0d916911a9622075a7258166ad0e13c891d524aca63de5d31e4ba97f6e0' 
  AND token = 'YADJq565KPPFbx1Yh3LI8S6zt6k+r93D7oWDxZRRArk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}