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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b5d0dfa404e8441c07ee50ad73ab0329730771c78d5b8e90288edee51c8a5d' 
  AND token = 'vddKAv3II3EBSePYbB/bLqcMraNeXAdx7b1qHyq+XbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}