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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6018ae86394d6503be45cd9bfa6d18f40b5357dfbd615b60d291dfe8c72c7cb3' 
  AND token = '/yEWXThI5GIg3o2l5vTTOkyNU8n29BH2nfmzKIY2gg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}