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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a0ea53ef25d6be1adb4f37303760406ce37744b6b6596c5a13814ca2daafd25' 
  AND token = 'veQY+Vk0k0HlGTFXcu5pEiKZuQkFX2m7Sb18R2oFMpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}