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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47944938f19eac33cc06e31cf3ed8d5de0557009b894eafe9848c126b854f1f2' 
  AND token = '/lh2+8/3vI63+sUjQO4zR2wPW1sdk2ubsIv2FBUB3JE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}