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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bf21843d5985cb696e14a8772343f3d93f9fada8c634a17db788888618dd8f8' 
  AND token = 'lSrqdOAWlQ7wzGxN0BsI381QqZHuFaFhWrLgLeUOtZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}