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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ea34b4ae7ec79f215e28402f24cba7fbb19548f99bb8e696e69929591d16b79' 
  AND token = 'BeRMj+TuzwRHtyTGC9cRHTGzZHFVE0ugIIWZc47yDaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}