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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4094daa800a0aa83cf2de0585924e536df4219e3c69e0ee1f635ad54dd8138ba' 
  AND token = 'zjCUUb06EKEsxHBkPzaR9+HCSMMnh+EZZPcRSVVB8Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}