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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f197d649234e3f8381ebbd370ef4348c7c86059e7e87bc5dc71e6727f50d993' 
  AND token = 'XkDXZ+mljxS6rS1Lr6w28UroPcQhysPmpaa1Q1z+T+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}