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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29cae0f4b56a398288b21520bf4f7d582f7c6e581ea12c6204469bd19699e375' 
  AND token = 'k6vcFxMlIcbz4BirKUeEdsWFPCZB4I2alTUSJMlr0gI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}