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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07de7e09695ad0473cd3c0e02cefd72bc56cbce3f52c18bd317f6bbfbd302378' 
  AND token = '9FFsFfGu8cGwPDzNJW5n7X8zbC+ZKSmCDQvMorLShL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}