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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4605482f790d885424e4be4208c8d57c41b0b289e228c10f1bf48d82ae33484' 
  AND token = '+1Vjf2hXiYGnS8iVlTcQAgqdHSz2iUPvq6c0U45Bxds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}