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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '889f53d1fe540ca3f4c165e806330c6460725b4051e4fda7439f088469255202' 
  AND token = 'OG7/7DQgWFb98VZMFxDo8E6eh2IqPD9BlfqksDP825g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}